Sunday, April 26, 2015

Leukemia: Signs & Symptoms



Sources: Leukemia & Lymphoma Society, NIH National Cancer Institute, &

Lewis, M.S., Dirksen, S., & Heitkemper, M.M. et al. (2014). Medical-surgical nursing: Assessment and management of clinical problems (9th ed.). St. Louis: Mosby. (LDH-9th)
Key Article/Source: LLS website

Sunday, April 19, 2015

Leukemia Pathophysiology

The below video series from Khan Academy is extremely helpful in explaining the pathophysiological process of leukemias. It begins with general pathophysiology of blood stem cells then moves into classifying the type of leukemia based on the affected stem cell group. The third and fourth videos provide more information on each the acute and chronic classifications of leukemias.





Sources: Khan Academy
Key Article: the above Khan Academy videos

Sunday, April 12, 2015

Leukemia Statistics & Epidemiology


New Cases of Leukemia: In 2014, 52,380 people are expected to be diagnosed with leukemia.
Prevalence: There are an estimated 327,520 people living with, or in remission from, leukemia in the US.

Survival
·      - The overall five-year relative survival rate for leukemia has more than quadrupled since 1960. From 1960 to 1963, the five-year relative survival rate among whites (only data available) with leukemia was 14 percent. From 1975 to 1977, the five-year relative survival rate for the total population with leukemia was 34.2 percent, and from 2004 to 2010, the overall relative survival rate was 60.3 percent.
·       - From 2004-2010, the five-year relative survival rates overall were
o   CML - 59.9 percent
o   CLL - 83.5 percent
o   AML - 25.4 percent overall and 66.3 percent for children and adolescents younger than 15 years
o   ALL - 70 percent overall, 91.8 percent for children and adolescents younger than 15 years, and 93 percent for children younger than 5 years.

Deaths
       - In 2014, 24,090 people are expected to die from leukemia (14,040 males and 10,050 females).

       - In 2007-2011, leukemia was the fifth most common cause of cancer deaths in men and the sixth most common in women in the US.
Below are the stories of two beautiful and strong current leukemia survivors. Testimonies such as theirs give us hope despite the intimidating numbers presented above.

Sources: Leukemia & Lymphoma Society and the American Cancer Society
Key article: LLS 2014-2015 Facts Sheet